Kneevive promotes healing of the knee joint

Non-Surgical Knee Treatment in Camp Hill, Pennsylvania.

Kneevive promotes healing of the knee joint

Non-Surgical Knee Treatment in Camp Hill, Pennsylvania.

Located in Camp Hill, Pennsylvania, Advanced PainCare is a premier destination for patients who demand more than pain management — they want real solutions. Led by Dr. Jean Louise Santo, our practice offers the KneeVive™ Program: a scientifically advanced, fully integrated approach to non-surgical knee restoration. Patients travel from across Central Pennsylvania to receive personalized, evidence-based care that addresses the root cause of knee pain rather than masking it with medication or rushing to surgery.

Avoid Knee Surgery & Restore Your Knee With the KneeVive Program

KneeVive™ is a comprehensive, injection-based regenerative treatment program that utilizes Regenexx® stem cell and platelet therapy to heal the knee joint from the inside out.

Cartilage breakdown, joint inflammation, and structural damage are common causes of chronic knee pain. Over time, these issues weaken the knee — leading to osteoarthritis, instability, and the progressive pain cycle that limits your daily life and the activities you love.

Regenexx® therapy uses a concentrated biologic solution drawn from your own body. When injected with precision imaging guidance into the damaged structures of the knee, it stimulates natural healing, reduces inflammation, and supports tissue regeneration.

KneeVive™ combines Regenexx® therapy with laser treatment, a custom exercise program, nutritional guidance, and body composition analysis — treating the whole patient, not just the joint. KneeVive™ is a comprehensive system — not a single treatment. Most patients begin to notice meaningful changes within 4–8 weeks.

Don’t Forget About The Rest of the Body – Treat the Whole Body With Regenexx

The knee joint doesn’t exist in isolation. The surrounding structures — hip joints, lumbar spine, ligaments, tendons, and supporting musculature — all influence knee mechanics and pain. A comprehensive approach to the whole body can provide the best long-term results.

Platelet-Rich Plasma (PRP) and Bone Marrow Concentrate are regenerative solutions derived from your own blood and bone marrow. When precisely injected into damaged joints, tendons, or spinal structures, the concentrated healing cells release bioactive proteins that resolve pain, reduce inflammation, and initiate tissue repair throughout the body.

Through Advanced PainCare’s full Regenexx® program, Dr. Santo is equipped to address pain and dysfunction throughout the entire musculoskeletal system — including:

Neck and back pain
Hip joint pain & arthritis
Shoulder injuries & rotator cuff
Sciatica & spinal conditions
Tendinitis & tendon tears
Sports injuries throughout the body

KneeVive™ is the starting point. Regenexx® at Advanced PainCare is the complete solution for patients who want to reclaim their whole body — not just their knee.

Find Out If You’re A Candidate >

About KneeVive

Knee Conditions Treated by KneeVive™:

Osteoarthritis (mild to severe)
Cartilage damage & degeneration
Meniscus tears & injuries
Ligament laxity & instability
Chronic knee pain & stiffness
Post-surgical knee pain
Tendinopathy & tendon damage
Knee pain limiting sports or daily activity

Long-Term Benefits of KneeVive™:

Reduce or eliminate chronic knee pain
Avoid or delay knee replacement surgery
Restore joint function & range of motion
Return to sports, hiking, golf, cycling & more
Maintain independence & quality of life
Reduce reliance on pain medications
Long-lasting results through tissue regeneration
No surgery, no hospital, no long recovery

A Common Cause of Chronic Knee Pain = Cartilage Breakdown & Joint Degeneration

The knee joint is lined with articular cartilage — a smooth, shock-absorbing surface that allows fluid, pain-free movement. When this cartilage begins to wear down, every step becomes painful.
Cartilage has very limited natural healing ability due to its poor blood supply. Once damaged, it rarely repairs itself without targeted intervention.
As cartilage degrades, the meniscus, ligaments, and surrounding tendons are placed under increasing strain — compounding instability and accelerating the degeneration cycle.
Bone-on-bone friction increases inflammation and stiffness in a cycle that conventional treatments — cortisone, PT, NSAIDs — can only temporarily interrupt.

Only a regenerative approach like KneeVive™ targets the actual biological repair of damaged knee tissue — stimulating natural healing where the body’s own supply falls short.

Find Out If You’re A Candidate >

What Makes Regenexx® Different From Standard PRP or Stem Cell Injections?

Regenexx® is not a kit.
Unlike standard PRP or stem cell packages used at most clinics, Regenexx® is a proprietary, research-backed protocol with over 20 years of outcome data and a global network of specialized physicians.
Precision matters.
Every procedure performed by Dr. Santo uses advanced imaging guidance to place cells exactly where they’re needed — not blind injections.
Lab-verified quality.
Regenexx® uses rigorous processing protocols — ensuring the concentration and viability of cells used in your treatment meets the highest standards.
The most studied orthobiologic network in the world.
Regenexx® providers contribute to one of the largest outcomes registries in regenerative orthopedics — meaning your treatment is informed by real patient data, not just theory.
Dr. Santo is a trained, credentialed Regenexx® provider.
One of a select network of physicians in Pennsylvania who meet the rigorous training and quality standards required to offer this protocol.

What Our Patients Are Saying

Real people, real results from Advanced PainCare’s regenerative treatments

Dr Santo listened to me when other doctors wouldn’t. The entire staff is just as fantastic, kind and compassionate. I am able to work full time again and have a full life thanks to the treatment I’ve received! I’m grateful beyond words.
Kelly V.

The staff and doctor are efficient and wonderful. They make me feel welcomed and comfortable during my visit and treatments. I am elated with the results from the laser treatment and I highly recommend their services!
Daniel B.

I have had prolotherapy twice before from another practitioner, and good results both times (knee and elbow). This was my first treatment by Dr Santo with Advanced pain Care, and there was minimal pain involved, a lot less than with the other practitioner.
Greg S.

Dr. Santo and the ladies are wonderful at Advanced PainCare and BioHealth Institute. They are caring and compassionate every single time I have gone in. Thank you for making my appointments smooth and in a safe environment.
Charlie J.

4 years and 3 subsequent PRP treatments, knee is working better than expected. Hiking 5+ miles on smooth grades no problem. Rocks on Appalachian trail pushed its limit, sore for 2 days.
Will do another PRP this year, see if further increase in performance.
John A.

I have been receiving help with constant pain from Dr. Santo at Advanced PainCare for more than 8 years now. Back, knee and leg pain can be so debilitating and limit not only your mobility. I am so very thankful for Dr. Santo and her competent, caring staff.
Vilma C.

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Meet Dr. Jean Louise Santo, MD

Dr. Santo is a member of a very selective, highly skilled interventional orthopedics network that is 100% focused on orthopedic conditions.

She is a musculoskeletal expert with extensive training and experience in the diagnosis and treatment of musculoskeletal conditions, as well as complex, image-guided injections of your body’s own healing agents to treat orthopedic issues.

Why Central PA Trusts Dr. Santo:

Board-certified Medical Doctor
Licensed Regenexx® Network Affiliate
Extensive training in regenerative orthopedics
Thousands of successful procedures performed
Trusted alternative to orthopedic surgery in Central PA

“My goal is to help you return to the activities you love without surgery. The KneeVive program represents the most advanced non-surgical approach to knee regeneration available today.”
– Dr. Jean Louise Santo, MD

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Advanced PainCare and BioHealth Institute
97 North 36th Street, Camp Hill, PA 17011
Phone: (717) 791-2860